Methyl 6-bromo-2-methylnicotinate

Name: Methyl 6-bromo-2-methylnicotinate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1227562-32-4
Cat. No. CS-0139262
Purity≥95%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 6-bromo-2-methylnicotinate|CS-0139262

Structure of 1227562-32-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Methyl 6-bromo-2-methylnicotinate is a brominated nicotinate ester featuring a methyl group at the 2-position and a bromine atom at the 6-position of the pyridine ring. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling efficient coupling reactions for the synthesis of functionalized pharmaceutical intermediates. The molecule exhibits enhanced reactivity in cross-coupling transformations due to the ortho-directing effect of the methyl group and the strong electron-withdrawing nature of the bromide. Its bench-stable solid form facilitates handling under standard laboratory conditions.

Application

Methyl 6-bromo-2-methylnicotinate serves as a versatile building block for the synthesis of substituted nicotinates and heterocyclic scaffolds. The bromine at the 6-position enables palladium-catalyzed cross-coupling reactions, while the methyl group at C2 enhances regioselectivity in electrophilic functionalization. Its bench-stable nature and compatibility with standard purification protocols facilitate efficient integration into medicinal chemistry and process development workflows.

General Information

CAS No. 1227562-32-4
Cat. No. CS-0139262
Purity ≥95%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈BrNO₂
Molecular Weight 230.06
Synonym(s) Methyl 6-bromo-2-methylpyridine-3-carboxylate
SMILES O=C(C1=CC=C(Br)N=C1C)OC

Computational Chemistry Data

TPSA 39.19
LogP 1.93912
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

Methyl 6-bromo-2-methylnicotinate sigmaMethyl 6-bromo-2-methylnicotinate manufacturerMethyl 6-bromo-2-methylnicotinate priceMethyl 6-bromo-2-methylnicotinate structureMethyl 6-bromo-2-methylnicotinate SDSbuy Methyl 6-bromo-2-methylnicotinateMethyl 6-bromo-2-methylnicotinate supplierMethyl 6-bromo-2-methylnicotinate usesMethyl 6-bromo-2-methylnicotinate molecular weightprice of Methyl 6-bromo-2-methylnicotinateMethyl 6-bromo-2-methylnicotinate chemical name formula of Methyl 6-bromo-2-methylnicotinate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 6-bromo-2-methylnicotinate

CAS No. 1227562-32-4

Recommended Products