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Structure of 1227572-43-1
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2,4-Dichloro-6-methoxypyridine features a pyridine core functionalized with chlorine atoms at positions 2 and 4 and a methoxy group at position 6, delivering enhanced reactivity and stability. This electron-deficient heterocycle serves as a key intermediate in pharmaceutical synthesis, particularly for kinase inhibitors and agrochemicals. The ortho-chloro arrangement facilitates nucleophilic substitution under mild conditions, while the para-methoxy group improves solubility and metabolic resistance.
2,4-Dichloro-6-methoxypyridine serves as a versatile building block in medicinal chemistry, enabling selective functionalization via nucleophilic substitution at the C2 or C4 positions. The methoxy group enhances solubility and modulates electronic properties, while the dichloro substitution pattern provides orthogonal reactivity for sequential coupling reactions. This compound exhibits good bench stability and facilitates efficient synthesis of heterocyclic scaffolds relevant to agrochemical and pharmaceutical development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: