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Structure of 1227580-92-8
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This electron-deficient dihydropyridine scaffold features a trifluoromethyl group that enhances metabolic stability and lipophilicity, while the carboxylic acid moiety enables direct conjugation or salt formation. The structural motif serves as a key building block in medicinal chemistry for bioactive heterocycles.
2-Oxo-6-(trifluoromethyl)-1,2-dihydropyridine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its conjugated enone system and electron-deficient pyridine core facilitate nucleophilic additions and transition-metal-catalyzed couplings. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid functionality allows for direct derivatization or salt formation, supporting purification and formulation. This compound demonstrates bench stability and compatibility with standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: