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Structure of 1227595-02-9
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Methyl 6-fluoro-2-methylnicotinate is a fluorinated pyridine ester featuring a methyl group at the 2-position and a fluoro substituent at the 6-position. This electron-deficient heterocycle integrates readily into synthetic routes for bioactive molecules, offering enhanced metabolic stability and favorable lipophilicity. The ester functionality enables straightforward derivatization under standard conditions.
Methyl 6-fluoro-2-methylnicotinate serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. Its ortho-substituted pyridine core facilitates electrophilic substitution and transition-metal-catalyzed coupling reactions. The methyl ester group offers convenient derivatization potential, while the 6-fluoro and 2-methyl substituents provide defined electronic and steric control, enhancing regioselectivity in downstream transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: