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Structure of 122773-97-1
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2-Phenylpyrimidine-5-carboxylic acid features a rigid heteroaromatic core fused to a phenyl ring and a carboxylic acid group, enabling versatile integration into bioactive scaffolds. The electron-deficient pyrimidine ring facilitates nucleophilic substitution, while the carboxylic acid offers direct conjugation or derivatization potential. This compound serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and other pharmaceutical agents.
2-Phenylpyrimidine-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its carboxylic acid group facilitates direct derivatization via amide coupling or esterification, while the pyrimidine core provides a rigid, planar platform for structure-activity studies. The phenyl substituent enhances π-stacking interactions and modulates electronic properties, offering favorable solubility and stability for downstream synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: