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Structure of 1228014-10-5
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This boronate-functionalized pyridine integrates a tetramethylboronate group and a silyl-protected alcohol, enabling stable coupling in Suzuki-Miyaura reactions. The trimethylsilyl ether offers enhanced stability during storage and handling, while the para-substituted pyridine serves as a robust directing group in transition metal catalysis.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2-((trimethylsilyl)oxy)propan-2-yl)pyridine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient palladium-catalyzed coupling under mild conditions, while the silyl ether-protected hydroxyl functionality offers orthogonal stability and selective deprotection. This dual-functional design facilitates modular synthesis of complex pyridine-based scaffolds with excellent bench stability and compatibility in multi-step sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: