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Structure of 1228078-57-6
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Elevated urinary levels of (R)-3-hydroxyisobutyric acid sodium correlate with metabolic dysfunction in 3-hydroxyisobutyric aciduria, a condition marked by impaired branched-chain amino acid catabolism and disrupted Krebs cycle flux. Sodium (R)-β-hydroxyisobutyrate (CAS 1228078-57-6) serves as a diagnostic metabolite reflecting aberrant mitochondrial dehydrogenase activity.
Sodium (R)-β-hydroxyisobutyrate (CAS 1228078-57-6) drives precise characterization of branched chain amino acid metabolic enzymes, particularly 3-hydroxyisobutyrate dehydrogenase and 3-hydroxyisobutyryl-CoA hydrolase. It enables stereospecific mechanistic analysis. Researchers rely on this enantiopure form to dissect reaction kinetics with high fidelity in metabolic pathway studies.
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Lot numbers can be found on the outside label of a product: