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Structure of 1228180-82-2
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4-(Pyridin-2-ylmethoxy)phenylboronic acid features a pyridin-2-ylmethoxy group attached to a phenylboronic acid scaffold, combining heterocyclic recognition with boronate reactivity. This configuration enhances solubility and stability in aqueous media while enabling efficient Suzuki-Miyaura coupling under mild conditions. The para-positioned boronic acid facilitates selective cross-coupling, and the pyridine moiety offers coordination potential for metal catalysts or supramolecular interactions. Ideal for constructing complex biaryl architectures in medicinal chemistry and materials science.
4-(Pyridin-2-ylmethoxy)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. The pyridinylmethyl ether moiety provides enhanced stability and solubility compared to simpler arylboronic acids, while the boronic acid group exhibits reliable reactivity under standard coupling conditions. Its functional group tolerance facilitates downstream modifications, making it well-suited for medicinal chemistry and materials synthesis applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: