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Structure of 1232152-74-7
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Tert-butyl 4-(but-3-yn-1-yl)piperazine-1-carboxylate features a terminal alkyne group appended to a piperazine scaffold, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation. The tert-butyl ester provides stability and ease of deprotection under mild acidic conditions, while the piperazine moiety offers favorable solubility and metabolic resilience. This reagent serves as a robust building block in click chemistry workflows.
Tert-butyl 4-(but-3-yn-1-yl)piperazine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to piperazine-based scaffolds via copper-catalyzed azide-alkyne cycloaddition (CuAAC). The terminal alkyne functionality facilitates conjugation with azides under mild conditions, while the tert-butyl carbamate group offers excellent stability and convenient deprotection. Its robustness and compatibility with diverse functional groups make it ideal for late-stage diversification in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: