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Structure of 123222-09-3
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Methyl 2-(2-chloropyridin-3-yl)acetate features a chloropyridine moiety linked to a methyl ester-functionalized acetyl group, enabling direct incorporation into heterocyclic synthesis. The electron-deficient pyridine ring enhances reactivity in nucleophilic substitution and coupling processes, while the ester handle supports further derivatization. This bench-stable compound serves as a key intermediate for pharmaceutical and agrochemical scaffolds.
Methyl 2-(2-chloropyridin-3-yl)acetate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-containing scaffolds via palladium-catalyzed cross-coupling reactions. The ortho-chloropyridine moiety facilitates direct functionalization, while the ester group offers compatibility with reduction, hydrolysis, and further derivatization. Its bench-stable, crystalline nature supports straightforward handling and purification, making it well-suited for iterative synthesis campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: