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Structure of 123278-03-5
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3-Chloro-2-iodobenzoic acid features a benzene ring bearing ortho-chloro and iodo substituents flanking a carboxylic acid group, enabling selective functionalization in cross-coupling reactions. This electron-deficient aryl halide delivers high reactivity under palladium catalysis while maintaining stability during handling and storage.
3-Chloro-2-iodobenzoic acid serves as a versatile building block for transition-metal-catalyzed cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation. The ortho-iodo and meta-chloro substituents provide complementary reactivity for sequential functionalization, while the carboxylic acid group offers direct handle for derivatization. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis of complex aromatic scaffolds in medicinal chemistry and materials development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: