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Structure of 1234616-33-1
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3-Iodo-1-methyl-1H-indazole-5-carboxylic acid features a sterically accessible indazole core bearing iodine and carboxylic acid groups at adjacent positions, enabling direct coupling in cross-coupling reactions. The methyl substitution enhances solubility and stability under standard conditions. This compound serves as a key building block for bioactive heterocycles in medicinal chemistry.
3-Iodo-1-methyl-1H-indazole-5-carboxylic acid serves as a versatile building block for C–H functionalization and cross-coupling reactions in medicinal chemistry. The iodide group enables palladium-catalyzed coupling with aryl, heteroaryl, and alkyl boranes or stannanes, while the carboxylic acid facilitates derivatization via amide formation or esterification. The 1-methyl substitution enhances stability and solubility, supporting straightforward purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: