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Structure of 1239355-46-4
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(R)-1-tert-Butyl 2-methyl aziridine-1,2-dicarboxylate is a chiral aziridine derivative featuring a sterically protected tert-butyl group and a methyl substituent. This configuration enables selective ring-opening reactions in asymmetric synthesis, where the strained three-membered ring integrates efficiently into complex molecular architectures under mild conditions.
(R)-1-tert-Butyl 2-methyl aziridine-1,2-dicarboxylate serves as a chiral building block for the synthesis of bioactive nitrogen-containing heterocycles. Its strained aziridine ring enables selective ring-opening reactions with nucleophiles under mild conditions, facilitating the installation of diverse functional groups. The tert-butyl and methyl substituents provide steric and electronic modulation, enhancing diastereoselectivity in asymmetric synthesis. Bench-stable and readily purified by chromatography, it functions effectively in standard coupling and cyclization protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: