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Structure of 1240568-16-4
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1-Cyclopropyl-4-nitro-1H-pyrazole features a rigid pyrazole core bearing a nitro group at the 4-position and a cyclopropyl substituent at nitrogen, delivering enhanced electron deficiency and steric profile. This combination enables robust participation in cross-coupling reactions and facilitates incorporation into bioactive scaffolds requiring precise electronic tuning.
1-Cyclopropyl-4-nitro-1H-pyrazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of pyrazole-based scaffolds with enhanced metabolic stability. The nitro group at C4 provides a handle for selective reduction or substitution, while the cyclopropyl substituent offers favorable steric and electronic properties. This compound exhibits bench stability, compatibility with common coupling reactions, and facilitates the synthesis of bioactive molecules through well-established functional group interconversions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: