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Structure of 1240620-65-8
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4-Bromo-2-fluoronicotinonitrile is a fluorinated nitrile-containing heterocycle featuring complementary halogen and cyano functionalities. This electron-deficient pyridine derivative enables direct coupling in cross-coupling reactions and serves as a key building block for pharmaceutical intermediates and functional materials.
4-Bromo-2-fluoronicotinonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its orthogonal reactivity—combining a bromide for coupling and a nitrile for functionalization—facilitates rapid diversification of pyridine-based scaffolds. The molecule exhibits excellent bench stability and compatibility with standard synthetic protocols, supporting efficient late-stage modifications in API development workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: