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Structure of 124170-06-5
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1-Fluoro-2-nitro-4-(trifluoromethoxy)benzene features a trifluoromethoxy group that enhances electron-withdrawal and metabolic stability, while the fluorine and nitro substituents enable selective electrophilic functionalization. This aryl halide serves as a robust scaffold for C–C and C–heteroatom bond formation under mild conditions.
1-Fluoro-2-nitro-4-(trifluoromethoxy)benzene serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its ortho-fluoro substitution and electron-withdrawing nitro and trifluoromethoxy groups. Its bench-stable nature and compatibility with diverse nucleophiles facilitate efficient synthesis of complex aryl scaffolds for API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: