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Structure of 1242258-49-6
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3-Fluoro-5-(trifluoromethoxy)benzoic acid features a strongly electron-withdrawing trifluoromethoxy group paired with a fluorine atom at the meta position, enhancing its utility in medicinal chemistry. This combination imparts high metabolic stability and improved membrane permeability. The carboxylic acid functionality enables direct coupling or derivatization in synthetic workflows.
3-Fluoro-5-(trifluoromethoxy)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its electron-deficient aromatic core enhances metabolic stability, while the carboxylic acid group facilitates direct coupling reactions or derivatization. The molecule exhibits excellent bench stability and compatibility with standard functional group transformations, making it well-suited for scalable synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P304+P340
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Lot numbers can be found on the outside label of a product: