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CS-W001157 4
Total: USD 88.00

1-(3-Bromophenyl)cyclopropane-1-carboxylic acid

  • CAS No. 124276-95-5

  • Cat. No. CS-0030381
  • Purity≥97%
  • MDL No.MFCD07374441
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

1-(3-Bromophenyl)cyclopropane-1-carboxylic acid|CS-0030381

Structure of 124276-95-5

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Description

This cyclopropane carboxylic acid derivative features a 3-bromophenyl group attached directly to the cyclopropane ring, delivering a rigid, electron-deficient aromatic moiety. The carboxylic acid functionality enables direct coupling reactions, while the strained three-membered ring imparts unique conformational constraints. Bench-stable and moisture-tolerant, it serves as a key building block for bioactive molecules in medicinal chemistry and materials science.

Application

1-(3-Bromophenyl)cyclopropane-1-carboxylic acid serves as a versatile building block for medicinal chemistry and materials science, enabling direct functionalization at the bromine site via palladium-catalyzed cross-coupling reactions. The cyclopropane carboxylic acid moiety provides structural rigidity and metabolic stability, while the ortho-brominated phenyl group offers predictable regiochemistry in Suzuki, Stille, and Negishi couplings. Bench-stable and amenable to standard purification methods, it facilitates efficient synthesis of complex aromatic scaffolds and biologically active compounds.

General Information

  • CAS No. 124276-95-5
  • Cat. No. CS-0030381
  • Purity ≥97%
  • MDL No. MFCD07374441
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉BrO₂
  • Molecular Weight 241.08
  • Synonym(s) Cyclopropanecarboxylic acid, 1-(3-bromophenyl)-
  • SMILES O=C(C1(C2=CC=CC(Br)=C2)CC1)O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.5653
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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