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Structure of 124276-95-5
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This cyclopropane carboxylic acid derivative features a 3-bromophenyl group attached directly to the cyclopropane ring, delivering a rigid, electron-deficient aromatic moiety. The carboxylic acid functionality enables direct coupling reactions, while the strained three-membered ring imparts unique conformational constraints. Bench-stable and moisture-tolerant, it serves as a key building block for bioactive molecules in medicinal chemistry and materials science.
1-(3-Bromophenyl)cyclopropane-1-carboxylic acid serves as a versatile building block for medicinal chemistry and materials science, enabling direct functionalization at the bromine site via palladium-catalyzed cross-coupling reactions. The cyclopropane carboxylic acid moiety provides structural rigidity and metabolic stability, while the ortho-brominated phenyl group offers predictable regiochemistry in Suzuki, Stille, and Negishi couplings. Bench-stable and amenable to standard purification methods, it facilitates efficient synthesis of complex aromatic scaffolds and biologically active compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: