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Structure of 124467-20-5
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2-Chloro-6-iodoquinoline is a halogenated quinoline scaffold featuring complementary reactive sites for cross-coupling. The chlorine and iodine substituents enable sequential functionalization, with the iodine group favoring palladium-catalyzed reactions under mild conditions. This compound serves as a strategic intermediate in the synthesis of bioactive heterocycles and advanced pharmaceutical candidates.
2-Chloro-6-iodoquinoline serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient access to substituted quinoline scaffolds. The orthogonal halogen reactivity—chlorine at C2 and iodine at C6—facilitates sequential functionalization under mild conditions. Its bench-stable nature and compatibility with Pd- and Ni-catalyzed couplings make it ideal for constructing complex heterocyclic architectures in medicinal chemistry and materials science workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: