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Structure of 124467-36-3
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2-Chloro-7,8-dihydroquinolin-5(6H)-one features a fused bicyclic core with a chlorinated aromatic ring and a reducible carbonyl at the 5-position. This scaffold delivers enhanced electron-withdrawing character and structural rigidity, enabling efficient incorporation into bioactive molecules. The compound exhibits bench-stable handling and compatibility with diverse synthetic transformations.
2-Chloro-7,8-dihydroquinolin-5(6H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds. Its reactive chloro substituent facilitates palladium-catalyzed cross-coupling reactions, while the enaminone functionality supports nucleophilic addition and condensation processes. The compound exhibits good bench stability and is readily purified by crystallization, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS05,GHS09
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335-H410
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Precautionary Statements : P261-P273-P280
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Lot numbers can be found on the outside label of a product: