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CS-W001157 4
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(7-Methyl-1H-indazol-5-yl)boronic acid

  • CAS No. 1245816-07-2

  • Cat. No. CS-0053120
  • Molecule weight175.98
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(7-Methyl-1H-indazol-5-yl)boronic acid|CS-0053120

Structure of 1245816-07-2

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General Information

  • CAS No. 1245816-07-2
  • Cat. No. CS-0053120
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BN₂O₂
  • Molecular Weight 175.98
  • Synonym(s) 7-Methyl-1H-indazole-5-boronic acid
  • SMILES CC1=C2NN=CC2=CC(=C1)B(O)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized indazoles with high efficiency. The methyl substituent enhances electron density at the heterocyclic core, improving reactivity and stability in synthetic workflows.

Application

(7-Methyl-1H-indazol-5-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its indazolyl scaffold provides robust stability and favorable solubility, while the boronic acid group exhibits excellent functional group tolerance and compatibility with diverse reaction partners. The methyl substituent enhances metabolic stability and modulates electronic properties, making it a practical choice for constructing biologically relevant heterocyclic architectures in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.14
  • LogP   -0.44888
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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