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Structure of 1245816-25-4
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3-Methyl-1H-indazol-5-yl-5-boronic acid features a boronic acid moiety integrated into a methyl-substituted indazolyl scaffold, enabling efficient Suzuki-Miyaura coupling reactions. The electron-rich aromatic system enhances reactivity, while the sterically accessible boron center facilitates reliable cross-coupling under standard conditions. This bench-stable reagent delivers precise structural incorporation in complex heterocyclic synthesis.
3-Methyl-1H-indazol-5-yl-5-boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. Its stability under ambient conditions and compatibility with diverse functional groups facilitate reliable synthesis of substituted indazoles. The boronic acid moiety enables direct coupling with aryl halides and triflates, making it particularly valuable for medicinal chemistry campaigns targeting kinase inhibitors and other heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: