1-(2,4-Dichloropyridin-3-yl)ethanone

Name: 1-(2,4-Dichloropyridin-3-yl)ethanone
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1246349-89-2
Cat. No. CS-0155131
Purity≥98%
MDL No.MFCD11847304

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(2,4-Dichloropyridin-3-yl)ethanone|CS-0155131

Structure of 1246349-89-2

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1246349-89-2
Cat. No. CS-0155131
Purity ≥98%
MDL No. MFCD11847304
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅Cl₂NO
Molecular Weight 190.03
Synonym(s) None
SMILES CC(=O)C1=C(Cl)N=CC=C1Cl

Description

1-(2,4-Dichloropyridin-3-yl)ethanone features a pyridine ring bearing two chlorine substituents at the 2- and 4-positions, creating a highly electron-deficient heterocyclic core. This structure integrates a ketone group at the 3-position, enabling direct coupling in cross-coupling reactions or nucleophilic addition processes. The compound exhibits enhanced stability under standard bench conditions and serves as a key intermediate in the synthesis of bioactive molecules and functionalized pharmaceuticals.

Application

1-(2,4-Dichloropyridin-3-yl)ethanone serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds. Its electrophilic acyl group facilitates nucleophilic substitution and condensation reactions, particularly in the synthesis of heterocyclic compounds. The 2,4-dichloro substitution pattern provides enhanced reactivity and orthogonal functionalization potential, while the ketone functionality offers stability and compatibility with standard purification methods. This compound functions effectively in late-stage modifications and is well-suited for scalable synthetic processes.

Synthesis

Route1
- 1246349-88-1
- ~80%
- In-stock
  
  1246349-89-2
References
- MEDICAL RESEARCH COUNCIL TECHNOLOGY; MCIVER, Edward, Giles; SMILJANIC, Ela; HARDING, Denise, Jamilla; HOUGH, Joanne Patent: WO2010/106333 A1, 2010 ; Location in patent: Page/Page column 71-72 ; WO 2010/106333 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 29.96
LogP 2.591
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Ketone

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

1-(2,4-Dichloropyridin-3-yl)ethanone sigma1-(2,4-Dichloropyridin-3-yl)ethanone manufacturer1-(2,4-Dichloropyridin-3-yl)ethanone price1-(2,4-Dichloropyridin-3-yl)ethanone structure1-(2,4-Dichloropyridin-3-yl)ethanone SDSbuy 1-(2,4-Dichloropyridin-3-yl)ethanone1-(2,4-Dichloropyridin-3-yl)ethanone supplier1-(2,4-Dichloropyridin-3-yl)ethanone uses1-(2,4-Dichloropyridin-3-yl)ethanone molecular weightprice of 1-(2,4-Dichloropyridin-3-yl)ethanone1-(2,4-Dichloropyridin-3-yl)ethanone chemical name formula of 1-(2,4-Dichloropyridin-3-yl)ethanone

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-(2,4-Dichloropyridin-3-yl)ethanone

CAS No. 1246349-89-2

Recommended Products