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Structure of 1246549-62-1
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7-Bromo-3-chloroquinoline is a halogenated quinoline scaffold featuring complementary electrophilic sites at the 7-bromo and 3-chloro positions. This electron-deficient heterocycle serves as a key building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of complex molecular architectures in medicinal chemistry and materials science.
7-Bromo-3-chloroquinoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogenation pattern. The bromo group at C7 facilitates Suzuki, Stille, or Negishi coupling, while the chloro group at C3 offers orthogonal reactivity for sequential functionalization. Its bench-stable crystalline form simplifies handling and purification, making it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: