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Structure of 1250411-83-6
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5-Bromo-2-fluoroisophthalonitrile features a rigid aromatic core with complementary electron-withdrawing nitrile and halogen groups. This combination enables selective coupling in cross-coupling reactions, offering enhanced reactivity and stability under standard conditions. The meta-directed substitution pattern facilitates regioselective functionalization in synthetic sequences.
5-Bromo-2-fluoroisophthalonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling the construction of substituted heterocycles via nucleophilic aromatic substitution or transition-metal-catalyzed coupling reactions. Its dual electron-withdrawing nitrile groups and orthogonal halogen functionalities facilitate selective functionalization, while its bench-stable nature supports reliable handling in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: