3-(tert-Butoxycarbonyl)-3-azabicyclo[3.2.1]octane-8-carboxylic acid

Name: 3-(tert-Butoxycarbonyl)-3-azabicyclo[3.2.1]octane-8-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1250997-29-5
Cat. No. CS-0051577
Purity≥98%
MDL No.MFCD17016674

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-(tert-Butoxycarbonyl)-3-azabicyclo[3.2.1]octane-8-carboxylic acid|CS-0051577

Structure of 1250997-29-5

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This azabicyclic scaffold integrates a tert-butoxycarbonyl-protected amine and a carboxylic acid handle, enabling direct incorporation into peptide macrocycles and constrained peptidomimetics. The rigid bicyclic core enhances conformational preorganization, while the orthogonal functional groups support sequential derivatization under standard coupling conditions.

Application

3-(tert-Butoxycarbonyl)-3-azabicyclo[3.2.1]octane-8-carboxylic acid serves as a versatile scaffold for the synthesis of nitrogen-containing heterocycles, particularly in medicinal chemistry applications. The protected amine and carboxylic acid functionalities enable orthogonal transformations, while the bicyclic core provides conformational rigidity. Its bench-stable tert-butyl ester facilitates straightforward deprotection and derivatization, supporting efficient access to diverse analogs via standard coupling and reduction protocols.

General Information

CAS No. 1250997-29-5
Cat. No. CS-0051577
Purity ≥98%
MDL No. MFCD17016674
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₂₁NO₄
Molecular Weight 255.31
Synonym(s) 3-Boc-3-azabicyclo[3.2.1]octane-8-carboxylic acid
SMILES OC([C@H]1[C@H]2CC[C@@H]1CN(C(OC(C)(C)C)=O)C2)=O

Computational Chemistry Data

TPSA 66.84
LogP 1.9641
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Bridge Rings compounds Other bridge ring compounds

Key Words

1250997-29-5 sigma1250997-29-5 manufacturer1250997-29-5 price1250997-29-5 structure1250997-29-5 SDSbuy 1250997-29-51250997-29-5 supplier1250997-29-5 uses1250997-29-5 molecular weightprice of 1250997-29-51250997-29-5 chemical name formula of 1250997-29-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-(tert-Butoxycarbonyl)-3-azabicyclo[3.2.1]octane-8-carboxylic acid

CAS No. 1250997-29-5

Recommended Products