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Structure of 1254034-35-9
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This difluoromethyl-substituted aryl bromide features a methoxy group at the ortho position, enabling seamless coupling in cross-coupling reactions. The electron-withdrawing difluoromethyl moiety enhances reactivity while maintaining bench stability under standard conditions.
4-Bromo-1-(difluoromethyl)-2-methoxybenzene serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable aryl bromide functionality. The difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, while the methoxy substituent provides orthogonal reactivity. This compound exhibits excellent bench stability and facilitates efficient synthesis of fluorinated heterocycles and bioactive scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: