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Structure of 1254319-51-1
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6-Bromo-2-methylisoindolin-1-one features a brominated isoindolinone core with a methyl group at the 2-position, enabling direct functionalization in cross-coupling reactions. This electron-deficient scaffold serves as a key intermediate in synthesizing bioactive molecules and pharmaceuticals.
6-Bromo-2-methylisoindolin-1-one serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C6 position via palladium-catalyzed cross-coupling reactions. The bromo group exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the isoindolinone core provides a rigid, electron-deficient scaffold suitable for target-oriented synthesis. Bench-stable and readily purified by flash chromatography, it functions as a key intermediate in the construction of bioactive heterocycles and API precursors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: