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CS-W001157 4
Total: USD 88.00

1H-Pyrazolo[4,3-b]pyridine-6-carboxylic acid

  • CAS No. 1256807-59-6

  • Cat. No. CS-0052508
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1H-Pyrazolo[4,3-b]pyridine-6-carboxylic acid|CS-0052508

Structure of 1256807-59-6

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Description

1H-Pyrazolo[4,3-b]pyridine-6-carboxylic acid is a heterocyclic scaffold featuring a fused pyrazole-pyridine core with a carboxylic acid group at the 6-position. This structure integrates electron-rich aromatic systems with a polar functional handle, enabling direct conjugation in medicinal chemistry applications. The molecule exhibits enhanced solubility and stability under standard reaction conditions, facilitating its use in drug discovery workflows.

Application

1H-Pyrazolo[4,3-b]pyridine-6-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused tricyclic core exhibits enhanced metabolic stability and π-conjugation, enabling efficient incorporation into bioactive scaffolds. The carboxylic acid functionality facilitates direct derivatization via amide coupling or esterification, supporting modular synthesis of drug candidates and functionalized polymers. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.

General Information

  • CAS No. 1256807-59-6
  • Cat. No. CS-0052508
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅N₃O₂
  • Molecular Weight 163.13
  • Synonym(s) 1H-Pyrazolo[4,3-b]pyridine-6-carboxylicacid
  • SMILES OC(=O)C1=CN=C2C=NNC2=C1

Computational Chemistry Data

  • TPSA   78.87
  • LogP   0.6561
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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