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Structure of 1256836-96-0
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Methyl 3-fluoro-5-hydroxypicolinate features a strategically positioned fluorine atom and hydroxyl group on the picolinate scaffold, enabling selective functionalization in synthetic sequences. This electron-deficient heterocycle integrates readily into bioactive molecule frameworks, offering enhanced metabolic stability and tailored solubility under standard conditions.
Methyl 3-fluoro-5-hydroxypicolinate serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. The ortho-fluoro and hydroxyl groups provide complementary reactivity for palladium-catalyzed couplings and regioselective derivatization. Bench-stable and readily purified by crystallization, it functions effectively in late-stage functionalization and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: