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Structure of 1258612-04-2
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4-(4-Chlorophenyl)picolinic acid features a conjugated aryl-pyridine scaffold with a para-chlorophenyl group enhancing electron-withdrawing character. This rigid, planar structure supports π-stacking interactions and facilitates metal coordination in supramolecular assemblies. The carboxylic acid moiety enables salt formation and conjugation with biomolecules.
4-(4-Chlorophenyl)picolinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its structure combines a picolinic acid core with a para-chlorophenyl substituent, offering enhanced metabolic stability and favorable electronic properties. The carboxylic acid group facilitates coupling reactions, while the chlorophenyl moiety supports further functionalization via cross-coupling or nucleophilic substitution. Bench-stable and readily purified, it functions effectively in standard synthetic workflows for API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: