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CS-W001157 4
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7-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carbonitrile

  • CAS No. 1260387-11-8

  • Cat. No. CS-0108815
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carbonitrile|CS-0108815

Structure of 1260387-11-8

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Description

7-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carbonitrile is a heterocyclic building block featuring a bromine at the 7-position and a nitrile group at the 3-position. This combination enables direct functionalization via cross-coupling or nucleophilic substitution, delivering access to diverse pyrrolopyridine derivatives for medicinal chemistry and materials applications. The molecule exhibits bench-stable handling characteristics and compatibility with standard reaction conditions.

Application

7-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carbonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromo and nitrile functionalities. The molecule exhibits excellent bench stability and facilitates efficient derivatization for heterocyclic scaffolds found in kinase inhibitors and CNS-targeted compounds. Its defined regiochemistry supports predictable transformations in multistep synthesis.

General Information

  • CAS No. 1260387-11-8
  • Cat. No. CS-0108815
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄BrN₃
  • Molecular Weight 222.04
  • Synonym(s) 7-Bromo-3-cyano-5-azaindole
  • SMILES N#CC1=CNC2=C1C=NC=C2Br

Computational Chemistry Data

  • TPSA   52.47
  • LogP   2.19708
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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