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Structure of 1260587-53-8
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Fmoc-2-fluoro-L-homophenylalanine integrates a fluorinated aromatic ring and a homophenylalanine backbone, enabling enhanced metabolic stability and conformational rigidity in peptide synthesis. This derivative facilitates the incorporation of bioorthogonal handles and improves membrane permeability in peptidomimetic design.
Fmoc-2-fluoro-L-homophenylalanine serves as a valuable building block in peptide synthesis, enabling the incorporation of fluorinated aromatic side chains with enhanced metabolic stability. The Fmoc group facilitates efficient N-terminal protection and easy removal under standard conditions, while the 2-fluoro substitution on the phenyl ring provides orthogonal reactivity and improved pharmacokinetic properties. This derivative functions effectively in solid-phase peptide synthesis, offering bench-stable handling, high coupling efficiency, and compatibility with diverse reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: