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Structure of 1260672-03-4
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5-Phenylmorpholin-3-one features a rigid, electron-deficient heterocyclic core that integrates seamlessly into kinase inhibitor scaffolds. The phenyl substituent enhances π-stacking interactions in target binding pockets, while the ketone group provides a key hydrogen bond acceptor site. This compound serves as a high-potency pharmacophore in targeted therapeutic development.
5-Phenylmorpholin-3-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles through standard functionalization at the C5 position. Its morpholinone core exhibits favorable stability and solubility, facilitating downstream transformations such as nucleophilic substitution and coupling reactions. The phenyl substituent enhances π-stacking potential and modulates lipophilicity, supporting its use in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: