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CS-W001157 4
Total: USD 88.00

7-Chloroquinoline-8-carbaldehyde

  • CAS No. 1260759-71-4

  • Cat. No. CS-0488759
  • Purity≥98%
  • MDL No.MFCD15526827
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Chloroquinoline-8-carbaldehyde|CS-0488759

Structure of 1260759-71-4

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Description

7-Chloroquinoline-8-carbaldehyde delivers a potent electrophilic aldehyde handle fused to an electron-deficient quinoline scaffold. This rigid, heteroaromatic platform enables direct integration into bioactive molecule architectures, particularly in medicinal chemistry campaigns targeting kinase inhibition and antiparasitic agents. The aldehyde group facilitates efficient condensation reactions under mild conditions.

Application

7-Chloroquinoline-8-carbaldehyde serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its electrophilic aldehyde functionality enables efficient coupling reactions, including reductive amination and Grignard additions, while the quinoline scaffold offers enhanced π-stacking and metabolic stability. Bench-stable and compatible with standard purification methods, it facilitates scalable access to advanced scaffolds in medicinal chemistry workflows.

General Information

  • CAS No. 1260759-71-4
  • Cat. No. CS-0488759
  • Purity ≥98%
  • MDL No. MFCD15526827
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆ClNO
  • Molecular Weight 191.61
  • Synonym(s) None
  • SMILES ClC1=C(C=O)C2=C(C=CC=N2)C=C1

Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.7007
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group :
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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