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Structure of 126120-87-4
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This difluorobenzo[d][1,3]dioxol-4-ylboronic acid features a sterically accessible boronate moiety integrated into a rigid, electron-deficient heteroaromatic scaffold. The ortho-difluoro substitution enhances metabolic stability and modulates electronic properties for efficient Suzuki-Miyaura coupling under standard conditions.
(2,2-Difluorobenzo[d][1,3]dioxol-4-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient access to fluorinated biaryls. The difluorophenyl moiety enhances metabolic stability and modulates electronic properties, while the boronic acid group offers excellent bench stability and compatibility with diverse reaction conditions. Its ortho-difluoro substitution pattern supports selective functionalization and is well-suited for medicinal chemistry applications involving aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: