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Structure of 1263045-16-4
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Mal-amido-PEG4-acid is a bifunctional linker featuring a maleimide group conjugated to a PEG4 spacer terminating in a carboxylic acid. This design enables site-specific bioconjugation via thiol-Michael addition, while the terminal acid facilitates further coupling reactions. The PEG4 segment provides enhanced solubility and reduced aggregation in aqueous environments.
Mal-amido-PEG4-acid serves as a versatile bifunctional linker for bioconjugation, combining the reactive maleimide group with a stable PEG4 spacer and carboxylic acid terminus. It enables site-specific conjugation to thiol-containing biomolecules while providing enhanced solubility and reduced non-specific binding. The PEG4 chain minimizes steric hindrance, facilitating efficient labeling in complex biological environments. Ideal for antibody-drug conjugate (ADC) synthesis and peptide modification workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: