3-Bromo-8-chloroimidazo[1,2-a]pyridine

Name: 3-Bromo-8-chloroimidazo[1,2-a]pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 1263058-56-5
Cat. No. CS-0212613
Purity≥98%
MDL No.MFCD22372514

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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3-Bromo-8-chloroimidazo[1,2-a]pyridine|CS-0212613

Structure of 1263058-56-5

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Description

3-Bromo-8-chloroimidazo[1,2-a]pyridine is a heterocyclic scaffold featuring complementary halogen substituents at the 3- and 8-positions, enabling selective cross-coupling reactions. This electron-deficient imidazopyridine integrates readily into medicinal chemistry libraries, offering enhanced metabolic stability and tunable polarity for drug discovery applications.

Application

3-Bromo-8-chloroimidazo[1,2-a]pyridine serves as a versatile building block in medicinal chemistry, enabling the construction of imidazopyridine scaffolds via palladium-catalyzed cross-coupling reactions. Its orthogonal halogenation pattern supports sequential functionalization, while its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient synthesis of complex heterocyclic architectures.

General Information

CAS No. 1263058-56-5
Cat. No. CS-0212613
Purity ≥98%
MDL No. MFCD22372514
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄BrClN₂
Molecular Weight 231.48
Synonym(s) None
SMILES C1=CN2C(=CN=C2C(=C1)Cl)Br

Computational Chemistry Data

TPSA 17.3
LogP 2.7502
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Bromo-8-chloroimidazo[1,2-a]pyridine

CAS No. 1263058-56-5

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