1-Bromo-3-(tert-butyl)-5-chlorobenzene

Name: 1-Bromo-3-(tert-butyl)-5-chlorobenzene
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1263377-20-3
Cat. No. CS-0435069
Purity≥97%
MDL No.MFCD18089328

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Bromo-3-(tert-butyl)-5-chlorobenzene|CS-0435069

Structure of 1263377-20-3

Size

Price

Quantity

* Please select Quantity before adding items.

Description

1-Bromo-3-(tert-butyl)-5-chlorobenzene features a sterically shielded tert-butyl group flanked by bromo and chloro substituents, enabling selective cross-coupling in complex molecule assembly. The electron-deficient aromatic core enhances reactivity in palladium-catalyzed transformations, while the bulky alkyl moiety minimizes undesired side reactions. This combination delivers high functional group tolerance and predictable regiochemistry under standard conditions.

Application

1-Bromo-3-(tert-butyl)-5-chlorobenzene serves as a versatile building block in cross-coupling reactions, enabling efficient construction of substituted biaryls and heterocycles. The bromo group facilitates palladium-catalyzed coupling with boronic acids, amines, and other nucleophiles, while the chloro substituent offers orthogonal reactivity under appropriate conditions. The tert-butyl group provides steric protection and enhances solubility, contributing to improved handling and purification. This compound is bench-stable, readily available, and well-suited for iterative synthetic strategies in medicinal chemistry and materials science.

General Information

CAS No. 1263377-20-3
Cat. No. CS-0435069
Purity ≥97%
MDL No. MFCD18089328
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₂BrCl
Molecular Weight 247.56
Synonym(s) 3-Bromo-5-chloro-tert-butylbenzene
SMILES CC(C1=CC(Cl)=CC(Br)=C1)(C)C

Computational Chemistry Data

TPSA 0
LogP 4.4
H_Acceptors 0
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H303-H315-H319-H412
Precautionary Statements : P264-P273-P280-P302+P352-P362-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1-Bromo-3-(tert-butyl)-5-chlorobenzene sigma1-Bromo-3-(tert-butyl)-5-chlorobenzene manufacturer1-Bromo-3-(tert-butyl)-5-chlorobenzene price1-Bromo-3-(tert-butyl)-5-chlorobenzene structure1-Bromo-3-(tert-butyl)-5-chlorobenzene SDSbuy 1-Bromo-3-(tert-butyl)-5-chlorobenzene1-Bromo-3-(tert-butyl)-5-chlorobenzene supplier1-Bromo-3-(tert-butyl)-5-chlorobenzene uses1-Bromo-3-(tert-butyl)-5-chlorobenzene molecular weightprice of 1-Bromo-3-(tert-butyl)-5-chlorobenzene1-Bromo-3-(tert-butyl)-5-chlorobenzene chemical name formula of 1-Bromo-3-(tert-butyl)-5-chlorobenzene

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-Bromo-3-(tert-butyl)-5-chlorobenzene

CAS No. 1263377-20-3

Recommended Products