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Structure of 126689-00-7
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This boronate ester features a sterically hindered tetramethylcyclopentadienyl core paired with a branched allylic substituent, delivering enhanced stability and compatibility in Suzuki-Miyaura cross-coupling reactions. The bulky methyl groups suppress protodeboronation, while the 2-methylprop-1-en-1-yl moiety enables efficient coupling under mild conditions.
4,4,5,5-Tetramethyl-2-(2-methylprop-1-en-1-yl)-1,3,2-dioxaborolane serves as a stable, bench-ready boron reagent for palladium-catalyzed cross-coupling reactions. Its sterically protected boronate moiety enables high functional group tolerance and reliable coupling with aryl, vinyl, and heteroaryl halides. The pendant isobutenyl group enhances solubility and facilitates purification, making it well-suited for iterative synthesis and late-stage functionalization in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: