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Structure of 126748-87-6
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1-Methyl-1H-1,2,4-triazole-3-carbaldehyde features a reactive aldehyde group tethered to a nitrogen-rich triazole core, enabling direct coupling in heterocyclic synthesis. This bench-stable scaffold integrates readily into bioactive molecule design, particularly where polar, electron-deficient motifs enhance target affinity or metabolic stability.
1-Methyl-1H-1,2,4-triazole-3-carbaldehyde serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its aldehyde functionality enables efficient imine formation, reductive amination, and coupling reactions with amines or hydrazines. The triazole core provides metabolic stability and hydrogen-bonding capacity, enhancing target affinity in bioactive molecules. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step syntheses of kinase inhibitors, antifungal agents, and other pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: