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Structure of 126822-39-7
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4-Cyclopropylpyrrolidin-2-one is a sterically constrained, bench-stable heterocycle featuring a cyclopropyl group at the 4-position and a ketone at C2. This configuration imparts enhanced metabolic stability and favorable lipophilicity, making it a valuable scaffold in medicinal chemistry for optimizing bioavailability and target engagement in CNS-directed therapeutics.
4-Cyclopropylpyrrolidin-2-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard amide and alkylation transformations. Its cyclopropyl substituent imparts conformational rigidity and enhanced metabolic stability, while the pyrrolidinone core offers excellent functional group tolerance and bench stability, facilitating straightforward purification and integration into diverse synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: