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Structure of 127169-17-9
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2-Benzylisoindoline-4-carboxylic acid features a rigid isoindoline scaffold bearing a benzyl group at the 2-position and a carboxylic acid at the 4-position, enabling integration into bioactive scaffolds. This structural motif offers enhanced metabolic stability and favorable solubility profiles for medicinal chemistry applications.
2-Benzylisoindoline-4-carboxylic acid serves as a versatile scaffold for the synthesis of isoindoline-based heterocycles, commonly employed in medicinal chemistry and materials science. The carboxylic acid group enables straightforward derivatization via amide coupling, esterification, or decarboxylation protocols. The benzyl substituent enhances stability and facilitates purification, while the isoindoline core provides a rigid, planar framework ideal for structure-activity studies. This compound functions effectively in standard peptide coupling and transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: