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Structure of 127709-19-7
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Methyl 2-(4-fluorophenyl)-2-hydroxyacetate features a benzylic hydroxyl group flanked by a fluorinated phenyl ring and an ester moiety, offering enhanced stability and controlled reactivity. This configuration enables efficient integration into complex synthetic sequences, particularly in the construction of chiral intermediates and bioactive scaffolds under standard bench conditions.
Methyl 2-(4-fluorophenyl)-2-hydroxyacetate serves as a versatile building block for the synthesis of chiral arylglycolic acid derivatives and pharmaceutically relevant heterocycles. The α-hydroxy ester functionality enables facile oxidation to the corresponding carboxylic acid or conversion to enol ethers, while the para-fluorophenyl group provides orthogonal reactivity for subsequent functionalization. Bench-stable and amenable to standard purification methods, it functions reliably in multistep syntheses requiring controlled stereochemistry and functional group compatibility.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: