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Structure of 127842-54-0
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3,4-Bis(difluoromethoxy)benzaldehyde features two difluoromethoxy groups positioned ortho to the aldehyde functionality, imparting enhanced electron-withdrawing character and improved metabolic stability. This aromatic aldehyde serves as a key building block in medicinal chemistry for constructing fluorinated pharmacophores. The molecule exhibits favorable solubility in common organic solvents and maintains stability under standard bench conditions, enabling straightforward integration into multistep synthetic sequences.
3,4-Bis(difluoromethoxy)benzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling the construction of bioactive heterocycles and functionalized aromatic scaffolds. Its dual difluoromethoxy groups enhance metabolic stability and modulate lipophilicity, while the aldehyde functionality facilitates straightforward derivatization via imine formation, reductive amination, or coupling reactions. The compound exhibits excellent bench stability and compatibility with standard purification techniques, making it well-suited for high-throughput synthesis and process-scale applications.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: