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Structure of 128405-69-6
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Cyclopropyl(2-hydroxyphenyl)methanone features a cyclopropyl group attached to a benzoyl scaffold bearing a phenolic hydroxyl at the ortho position. This structural motif imparts enhanced rigidity and polarity, facilitating integration into bioactive scaffolds. The molecule exhibits favorable solubility profiles and stability under standard handling conditions, making it suitable for medicinal chemistry applications involving hydrogen bonding or metal coordination.
Cyclopropyl(2-hydroxyphenyl)methanone serves as a versatile building block in medicinal chemistry, enabling direct incorporation of a phenolic hydroxyl group adjacent to a ketone functionality. Its structure facilitates downstream transformations such as reductive amination, nucleophilic addition, and transition-metal-catalyzed coupling reactions. The cyclopropyl moiety provides enhanced metabolic stability and conformational rigidity, while the ortho-hydroxyketone system supports intramolecular coordination in metal complexes. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step synthesis of bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: