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Structure of 1289043-16-8
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2-Fluoro-3-formylbenzoic acid features a strategically positioned formyl group adjacent to a fluorinated benzene ring, enabling direct integration into diverse synthetic scaffolds. This electron-deficient aryl aldehyde pairs readily with nucleophiles in condensation reactions, offering efficient access to functionalized heterocycles and bioactive intermediates under standard conditions.
2-Fluoro-3-formylbenzoic acid serves as a versatile bifunctional building block in medicinal chemistry, enabling direct incorporation of both formyl and carboxylic acid functionalities into complex scaffolds. Its ortho-fluoro substituent enhances electrophilicity at the formyl group and facilitates downstream derivatization via nucleophilic addition or reductive amination. The compound exhibits good bench stability and is compatible with standard coupling and protection protocols, supporting efficient synthesis of heterocyclic systems and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: