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CS-W001157 4
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2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid

  • CAS No. 1289942-66-0

  • Cat. No. CS-M2260
  • Purity≥98%
  • MDL No.MFCD22581651

*For research and further manufacturing use only, not for direct human use.

2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid|CS-M2260

Structure of 1289942-66-0

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General Information

  • CAS No. 1289942-66-0
  • Cat. No. CS-M2260
  • Purity ≥98%
  • MDL No. MFCD22581651
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅FN₂O₃
  • Molecular Weight 254.26
  • Synonym(s) None
  • SMILES FC1=C(C(NC)=O)C=CC(NC(C(O)=O)(C)C)=C1

Description

This fluoro-substituted aryl amide integrates a methylcarbamoyl group and sterically hindered tert-butyl carboxylic acid functionality, enabling robust conjugation in bioconjugate applications under standard conditions.

Application

2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid serves as a versatile building block for medicinal chemistry campaigns, enabling the construction of bioactive heterocyclic scaffolds. Its ortho-fluorinated aryl amine and sterically hindered α-amino acid motif facilitate coupling reactions and offer enhanced metabolic stability. The molecule exhibits good bench stability and compatibility with standard purification methods, making it suitable for iterative synthesis in API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   78.43
  • LogP   1.4604
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   4

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