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Structure of 129560-99-2
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4-(2,2,2-Trifluoroethoxy)phenol features a trifluoromethyl ether linkage that enhances metabolic stability and lipophilicity. The para-positioned phenolic hydroxyl group enables direct functionalization in coupling reactions. This compound integrates readily into bioactive scaffolds requiring electron-withdrawing substituents and exhibits robust performance under standard bench conditions.
4-(2,2,2-Trifluoroethoxy)phenol serves as a valuable building block in medicinal chemistry and materials science, offering enhanced lipophilicity and metabolic stability due to the trifluoromethyl group. The phenolic hydroxyl enables straightforward derivatization via etherification or esterification, while the trifluoroethoxy substituent provides good bench stability and compatibility with standard synthetic protocols. Its structure facilitates incorporation into bioactive heterocycles and functional polymers.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: