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Structure of 129747-52-0
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Methyl 5-(hydroxymethyl)nicotinate features a pyridine ring bearing a methyl ester and a pendant hydroxymethyl group, enabling direct functionalization at the C5 position. This bench-stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring polar, electron-deficient heterocycles. The hydroxymethyl moiety serves as a versatile handle for derivatization via oxidation, protection, or coupling reactions.
Methyl 5-(hydroxymethyl)nicotinate serves as a versatile building block for pyridine-based heterocycles and bioactive molecules. The pendant hydroxymethyl group enables selective oxidation to carboxylic acid, reductive functionalization, or ether formation, while the ester moiety supports cross-coupling reactions and nucleophilic substitutions. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient access to pharmaceutical intermediates and agrochemical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: